Date of Award

2025

Document Type

Thesis

Degree Name

Bachelors

Department

Natural Sciences

First Advisor

Clore, Amy

Area of Concentration

Biology

Abstract

Epilepsy is a condition with excessive neuronal firing in the brain leading to seizures. While various genetic mutations and treatment approaches are relevant to epilepsy, particular attention is given to how dysfunction of the gene Leucine-rich gliomainactivated protein 1 affects neural communication and promotes epileptic activity. Pharmacological approaches to treatments are analyzed. The ketogenic diet, a high-fat, low-carbohydrate dietary intervention, is also explored for its potential therapeutic role. Although further investigation is necessary, current insights suggest the ketogenic diet may significantly reduce seizure frequency, offering a promising direction for future treatment strategies, especially in patients who do not respond well to medications.

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