Author

Gavin Zitman

Date of Award

2018

Document Type

Thesis

Degree Name

Bachelors

Department

Natural Sciences

First Advisor

Ryba, Tyrone

Area of Concentration

Biology

Abstract

DNA microarrays are a technology that developed rapidly in the 1990s, transforming and advancing certain areas of research in the biological sciences, specifically gene expression profiling. The effects of this technology on the field of dentistry through techniques such as global gene expression profiling has been the topic of much research in the past five years. Several recent experiments have shed light on this technology’s abilities and potential to improve patient outcomes. Numerous recent studies have demonstrated their possible effects on the study of both oral cancer and dental caries. Advances in microarrays have allowed for millions of data points to be generated from single experiments, often prompting new hypotheses for the genetic effects on oral health problems. This paper intends to discuss the general concepts behind DNA microarrays and provide an understanding of its potential as a tool in dental medicine.

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