Date of Award

5-2026

Document Type

Thesis

Degree Name

Bachelor of Arts (BA)

Department

Natural Sciences

First Advisor

Fennie, Kristopher

Area of Concentration

Biology

Abstract

32 studies were evaluated in determining detection of immune dysregulation, derived from monocyte, T-cell, B-cell, and protein panels, and identifying trends in disorder-specific biomarker data for different psychiatric conditions including, ASD, schizophrenia, MDD, bipolar disorder, GAD, OCD, ADHD, and C-PTSD. The studies selected reporting significant immune abnormalities from biomarker data, with observed findings of immune dysregulation in psychiatric populations frequently coincided with the prevalence of comorbid physical issues, such as metabolic imbalances, cardiovascular conditions, and gastrointestinal issues. These observations highlight the intersection of altered biomarker variation and comorbid disease outcomes present in individuals (including their sex) with psychiatric conditions compared to those without. This highlights the opportunity and importance of conducting further research in preventative measures to reduce the severity of mental condition symptoms and lower the likelihood of immune dysfunction from occurring.

Rights

The author has granted New College of Florida the nonexclusive right to archive, make accessible, and distribute for educational purposes this work in whole or in part in all forms of media, now or hereafter known. The copyright of this work remains with the author.

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