Cellular and Genetic Factors in Traumatic Brain Injury: A Histological Analysis

Date of Award

2009

Document Type

Thesis

Degree Name

Bachelors

Department

Natural Sciences

First Advisor

Demski, Leo

Keywords

Biology, Neurobiology, Brain Injury

Area of Concentration

General Studies

Abstract

Traumatic brain is a growing concern among the general population with debilitating long -term effects. The introduction in the thesis will review other literature on traumatic brain injury to give the reader a brief overview of the topic. I hypothesized that traumatic brain injury has a profound effect on physiological activity. I also hypothesized that there is genetic influence on the outcome of injury as well. I performed histological analyses on brain tissues of mice that have undergone traumatic brain injury experiments at the Roskamp Institute. The results from my analyses have indicated that both traumatic brain injury and genetic factors do have a substantial effect on the overall outcome.

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